Cathepsin S Substrate - 1 mg
- Cat.Number : AS-61859
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Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin S is a cysteine proteinase involved in the pathogenesis of autoimmune diseases, atherosclerosis, cancer, obesity and related diseases.
This peptide is a cathepsin S substrate fluorescently labeled with AMC (Ex/Em=354 nm/442 nm). It can be used to measure cathepsin S activity.
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Citations
A parasite cysteine protease is key to host protein degradation and iron acquisition.
J Biol Chem . 2008 Aug 13 ; 283(43) 28934 | DOI : 10.1074/jbc.M805824200
- T. O'Brien
References
Potent and Selective Inhibition of Human Cathepsin K Leads to Inhibition of Bone Resorption In Vivo in a Nonhuman Primate
J Bone Miner Res . 2001 Oct 01 ; 16(10) 1739 | DOI : https://doi.org/10.1359/jbmr.2001.16.10.1739
- G. Stroup
- et al