IMG-EN-AS-28310-01.jpg
Peptides

CEF1, Influenza Matrix Protein M1 (58-66) - 1 mg

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  • Cat.Number : AS-28310
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HLA-A*02-restricted epitope from influenza matrix protein (58-66). The CD8 T-cell response against this epitope is immunodominant when restriced by HLA-A*02, a MHC molecule expressed by approximately half of the human population.

Specifications

Chemistry
Sequence one letter code
  • GILGFVFTL
Sequence three letter code
  • H-Gly-Ile-Leu-Gly-Phe-Val-Phe-Thr-Leu-OH
CAS registry number
  • 141368-69-6
Molecular Formula
  • C49H75N9O11
Molecular Mass/ Weight
  • 966.3
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Influenza

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Citations

Sperm-derived SPANX-B is a clinically relevant tumor antigen that is expressed in human tumors and readily recognized by human CD4+ and CD8+ T cells.

Clin. Cancer Res. . 2009 Mar 10 ; 15(6) 1954 | DOI : 10.1158/1078-0432.CCR-08-1290

  • G. Almanzar

References

The Human CD8 Coreceptor Effects Cytotoxic T Cell Activation and Antigen Sensitivity Primarily by Mediating Complete Phosphorylation of the T Cell Receptor ζ Chain

J. Biol. Chem . 2001 Aug 01 ; 276(35) 32786 | DOI : https://doi.org/10.1074/jbc.M102498200

  • M. Purbhoo
  • et al