Cyclo (-RGDfK) - 1 mg
- Cat.Number : AS-61111
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In one study where this peptide was labeled with 125I, it was found to bind specifically and with high affinity to αvβ3 receptors on neovascular blood vessel sections of different major human cancers. The integrin alpha(IIb)beta(3)-specific cyclic hexapeptide contains an Arg-Gly-Asp (RGD) sequence.
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Citations
RGD-functionalisation of PLLA nanofibers by surface coupling using plasma treatment: influence on stem cell differentiation.
J Mater Sci Mater Med . 2009 Nov 27 ; 21(4) 1363 | DOI : 10.1007/s10856-009-3947-2
- J. Paletta
The therapeutic response to multifunctional polymeric nano-conjugates in the targeted cellular and subcellular delivery of doxorubicin.
Biomater . 2009 Oct 08 ; 31(4) 757 | DOI : 10.1016/j.biomaterials.2009.09.080
- X. Xiong
Tumor-targeted HPMA copolymer-(RGDfK)-(CHX-A″-DTPA) conjugates show increased kidney accumulation.
J Controlled Release . 2008 Jul 18 ; 132(3) 193 | DOI : 10.1016/j.jconrel.2008.07.014
- M. Borgman
References
Evaluation of a Radiolabelled Cyclic DTPA-RGD Analogue for Tumour Imaging and Radionuclide Therapy
Int J Cancer . 2000 Sep 13 ; 90(4) 186 | DOI : https://doi.org/10.1002/1097-0215(20000820)90:4<186::AID-IJC2>3.0.CO;2-P
- PM. Van Hagen
- et al