Fibronectin-Laminin a1 Fusion Peptide, FN-A208 - 1 mg
- Cat.Number : AS-65007
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This peptide is a fusion of A208, derived from murine laminin a1, and the active site of fibronectin (GRGDS), with a glycine spacer. This peptide forms amyloid-like fibrils and promotes formation of actin stress fibers that mediate fibroblast cell attachment, offering it potential as a bioadhesive for tissue regeneration and engineering. FN-A208 interacts with IKVAV receptors and integrins. Its activity is disrupted by the presence of EDTA.
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References
Design and activity of multifunctional fibrils using receptor-specific small peptides
Biomater . 2009 Dec 01 ; 30(35) 6731 | DOI : https://doi.org/10.1016/j.biomaterials.2009.08.044
- Y. Ohga
- et al
Multifunctional peptide fibrils for biomedical materials
Biopolymers Pept. Sci . 2004 Feb 06 ; 76(1) 27 | DOI : https://doi.org/10.1002/bip.10565
- S. Kasai
- et al