Peptides

Fibronectin-Laminin a1 Fusion Peptide, FN-A208 - 1 mg

$107.00
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  • Cat.Number : AS-65007
  • Availability :
    In stock

Quantity

This peptide is a fusion of A208, derived from murine laminin a1, and the active site of fibronectin (GRGDS), with a glycine spacer. This peptide forms amyloid-like fibrils and promotes formation of actin stress fibers that mediate fibroblast cell attachment, offering it potential as a bioadhesive for tissue regeneration and engineering. FN-A208 interacts with IKVAV receptors and integrins. Its activity is disrupted by the presence of EDTA.

Specifications

Chemistry
Sequence one letter code
  • GRGDSGAASIKVAVSADR
Sequence three letter code
  • H-Gly-Arg-Gly-Asp-Ser-Gly-Ala-Ala-Ser-Ile-Lys-Val-Ala-Val-Ser-Ala-Asp-Arg-OH
Molecular Formula
  • C69H121N25O26
Molecular Mass/ Weight
  • 1717
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • murine

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References

Design and activity of multifunctional fibrils using receptor-specific small peptides

Biomater . 2009 Dec 01 ; 30(35) 6731 | DOI : https://doi.org/10.1016/j.biomaterials.2009.08.044

  • Y. Ohga
  • et al

Multifunctional peptide fibrils for biomedical materials

Biopolymers Pept. Sci . 2004 Feb 06 ; 76(1) 27 | DOI : https://doi.org/10.1002/bip.10565

  • S. Kasai
  • et al