IMG-EN-AS-23520-01.jpg
Peptides

Cys-beta-Amyloid (1-40) - 1 mg

$394.00
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  • Cat.Number : AS-23520
  • Availability :
    In stock

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Aß (1-40) together with Aß (1-42) are two major C-terminal variants of the Aß protein constituting the majority of Aßs. These undergo post-secretory aggregation and deposition in the Alzheimer’s disease brain. This Cys-containing mutant can be used as a model for aggregation studies.

Specifications

Chemistry
Sequence one letter code
  • CDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
Sequence three letter code
  • H-Cys-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH
CAS registry number
  • 208266-35-7
Molecular Formula
  • C197H300N54O59S2
Molecular Mass/ Weight
  • 4433.3
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

Prevention of β-Amyloid Neurotoxicity by Blockade of the Ubiquitin—Proteasome Proteolytic Pathway

J Neurochem . 2000 Sep 01 ; 75(3) 1258 | DOI : https://doi.org/10.1046/j.1471-4159.2000.0751258.x

  • A. Favit
  • et al