Peptides

Bradykinin; Angiotensin I Converting Enzyme (ACE I) Inhibitor

  • Cat.Number : AS-20667
  • Availability :
    In stock

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This peptide is an inhibitor for Angiotensin I Converting Enzyme (ACE I), derived from Bradykinin. ACE I partially suppresses the renin-angiotensin-aldosterone system (RAAS), which regulates blood pressure and may mediate hypertension. ACE I converts angiotensin I to the biologically active peptide angiotensin II using a zinc- and chloride- dependent mechanism.

Specifications

Chemistry
Sequence one letter code
  • RPPGFSPFR
Sequence three letter code
  • H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH
CAS registry number
  • 58-82-2
Molecular Formula
  • C50H73N15O11
Modification
Conjugation
  • Unconjugated
Storage & stability
Form
  • Lyophilized
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • frog

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Citations

The use of acetone as a substitute for acetonitrile in analysis of peptides by liquid chromatography/electrospray ionization mass spectrometry.

Rapid Comm Mass Spectrom . 2010 Jan 01 ; 24(1) 6 | DOI : 10.1002/rcm.4352

  • T. Keppel

References

Blocking the RAAS at different levels: an update on the use of the direct renin inhibitors alone and in combination

Vasc Health Risk Manag . 2010 Aug 09 ; 6 549 | DOI : 10.2147/vhrm.s11816

  • F. Cagnoni
  • et al

Angiotensin-I-converting enzyme and its relatives

Genome Biol . 2003 Jul 25 ; 4 225 | DOI : https://doi.org/10.1186/gb-2003-4-8-225

  • J. Riordan
  • et al