Peptides

flg22, Flagellin Fragment - 1 mg

$221.00
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  • Cat.Number : AS-62633
  • Availability :
    In stock

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This is 22 amino acids flagellin peptide known as flg2. It spans the core domain necessary for binding and biological activity in plant cells. This peptide spanning the 22 amino acids in the core of the conserved domain induces responses after treatment with fungal elicitors such as chitin fragments, xylanase, ergosterol, and high-mannose–type glycopeptides when applied in subnanomolar concentrations. Flagellin is the structural protein that forms the major portion of flagellar filaments. Flagellins from different bacterial species vary in their central part but show conservation of their N-terminal and C-terminal regions.

Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.

Specifications

Chemistry
Sequence one letter code
  • QRLSTGSRINSAKDDAAGLQIA
Sequence three letter code
  • H-Gln-Arg-Leu-Ser-Thr-Gly-Ser-Arg-Ile-Asn-Ser-Ala-Lys-Asp-Asp-Ala-Ala-Gly-Leu-Gln-Ile-Ala-OH
Molecular Formula
  • C93H162N32O34
Molecular Mass/ Weight
  • 2272.7
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • bacteria

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Citations

Plasma membrane order and fluidity are diversely triggered by elicitors of plant defence

J Exp Bot . 2016 Jul 18 ; 67(17) 5173 | DOI : 10.1093/jxb/erw284

  • R. Sandor

OsMPK6 plays a critical role in cell differentiation during early embryogenesis in Oryza sativa

J Exp Bot . 2016 Feb 24 ; 67(8) 2425 | DOI : 10.1093/jxb/erw052

  • J. Yi

Functional characterization of the two ferrochelatases in Arabidopsis thaliana.

Plant Cell Environ . 2014 Jan 15 ; 38(2) 280 | DOI : 10.1111/pce.12248.

  • M. Scharfenberg

References

Bacterial flagellins: mediators of pathogenicity and host immune responses in mucosa

Trends Microbiol . 2004 Nov 01 ; 12(11) 509 | DOI : https://doi.org/10.1016/j.tim.2004.09.002

  • H. Ramos
  • et al

The Bacterial Elicitor Flagellin Activates Its Receptor in Tomato Cells According to the Address–Message Concept

Plant Cell . 2000 Sep 01 ; 12(9) 1783 | DOI : https://doi.org/10.1105/tpc.12.9.1783

  • T. Meindl
  • et al