Peptides

Plasmepsin V FRET Substrate - 1 mg

$237.00
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  • Cat.Number : AS-64939
  • Availability :
    In stock

Quantity

This FRET substrate peptide for Plasmepsin V (PMV) is derived from the conserved Plasmodium Export Element (PEXEL) motif of Histidine-Rich Protein II (HRPII). PMV is an ER aspartic protease that recognizes and cleaves the RXL sequence within the PEXEL motif of proteins exported by human malaria parasite Plasmodium falciparum, allowing them to translocate into host erythrocytes.

Specifications

Chemistry
Sequence one letter code
  • Dabcyl-LNKRLLHETQ-EDANS
Sequence three letter code
  • Dabcyl-Leu-Asn-Lys-Arg-Leu-Leu-His-Glu-Thr-Gln-EDANS
Molecular Formula
  • C81H120N23O20S1
Molecular Mass/ Weight
  • 1751.1
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Application
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Plasmodium

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References

Plasmepsin V licenses Plasmodium proteins for export into the host erythrocyte

Nature . 2010 Feb 04 ; 463(7281) 632 | DOI : 10.1038/nature08726

  • I. Russo
  • et al