IMG-EN-AS-61515-01.jpg
Peptides

GAD65 (206-220) - 1 mg

$148.00
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  • Cat.Number : AS-61515
  • Availability :
    In stock

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A Glutamic acid decarboxylase 2 (GAD2) peptide corresponding to residues 206 to 220 of GAD65. GAD2 is presented to T cells in association with I-Ag7 MHC class II molecules. This peptide was also used as a part of Ig chimeras to test whether IL-10 interferes with expression of CTLA-4.

Specifications

Chemistry
Sequence one letter code
  • TYEIAPVFVLLEYVT
Sequence three letter code
  • H-Thr-Tyr-Glu-Ile-Ala-Pro-Val-Phe-Val-Leu-Leu-Glu-Tyr-Val-Thr-OH
Molecular Formula
  • C86H129N15O24
Molecular Mass/ Weight
  • 1757.2
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human, mouse, rat, bovine, pig

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References

IL-10 Diminishes CTLA-4 Expression on Islet-Resident T Cells and Sustains Their Activation Rather Than Tolerance

J Immunol . 2005 Jan 15 ; 174(2) 662 | DOI : https://doi.org/10.4049/jimmunol.174.2.662

  • R. Gregg
  • et al