Peptides
[Gln22]-beta-Amyloid (1-40), Dutch Mutation - 0.5 mg
$228.00
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- Cat.Number : AS-61261
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Several mutations within the β-amyloid precursor gene cause early onset familial Alzheimer's disease, and were shown to promote Aβ aggregation. In the dutch mutant, Glu 22 is replaced with Gln, leading to rapid formation of neuroteoxic aggregates with higher proteolysis resistance.
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Citations
Vascular cell lines expressing SSAO/VAP‐1: a new experimental tool to study its involvement in vascular diseases.
Biol Cell . 2011 Nov 01 ; 103(11) 543 | DOI : 10.1042/BC20110049
- M. Sole
- M. Unzeta