Peptides

gp91 ds-tat, FAM labeled - 0.5 mg

$175.00
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  • Cat.Number : AS-63852
  • Availability :
    In production

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Quantity

This FAM labeled peptide (Abs/Em=492/518 nm) is composed of gp91phox sequence linked to the human immunodeficiency virus (HIV)-tat peptide. The tat sequence facilitates the entry of this peptide into all cells. It is used as a peptide inhibitor for NADPH oxidase assembly.

Specifications

Chemistry
Sequence one letter code
  • 5-FAM-YGRKKRRQRRRCSTRIRRQL-NH2
Sequence three letter code
  • 5-FAM-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Cys-Ser-Thr-Arg-Ile-Arg-Arg-Gln-Leu-NH2
Molecular Formula
  • C130H212N52O31S1
Molecular Mass/ Weight
  • 3031.6
Properties
Absorbance (nm)
  • 492
Emission (nm)
  • 518
Modification
Conjugation type
  • Fluorescent dyes
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C Protected from light
Activity
Application
Biomarker Target
Detection Method
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • HIV

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References

NADPH Oxidase-Derived Reactive Oxygen Species Mediate the Cerebrovascular Dysfunction Induced by the Amyloid β Peptide

J Neuroscience . 2005 Feb 16 ; 25(7) 1769 | DOI : https://doi.org/10.1523/JNEUROSCI.5207-04.2005

  • L. Park

Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein

PNAS . 2008 Jan 29 ; 105(4) 1347 | DOI : https://doi.org/10.1073/pnas.0711568105

  • L. Park
  • et al