Peptides

GRGDSPK - 1 mg

  • Cat.Number : AS-61109
  • Availability :
    In stock

Quantity

A linear integrin binding peptide. It inhibits endothelial cell adhesion to fibroblast growth factor-2 and to fibronectin.

Specifications

Chemistry
Sequence one letter code
  • GRGDSPK
Sequence three letter code
  • H-Gly-Arg-Gly-Asp-Ser-Pro-Lys-OH
CAS registry number
  • 111119-28-9
Molecular Formula
  • C28H49N11O11
Molecular Mass/ Weight
  • 715.8
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • synthetic

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References

Inhibition of Angiogenesis and Tumor Growth by SCH221153, a Dual alpha(v)beta3 and alpha(v)beta5 Integrin Receptor Antagonist

Cancer Res . 2001 Mar 01 ; 61(5) 2232 | DOI : PMID: 11280792

  • C. Kumar
  • et al

αvβ3 Integrin Mediates the Cell-adhesive Capacity and Biological Activity of Basic Fibroblast Growth Factor (FGF-2) in Cultured Endothelial Cells

MBC . 2017 Oct 13 ; 8(12) 2449 | DOI : 10.1091/mbc.8.12.2449

  • M. Rusnati