Human MMP-3 - 100 µL
- Cat.Number : AS-72006
- Manufacturer Ref. :
-
Availability :
In stock
- Shipping conditions : Ice fees will apply
Alternative choices
Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated zinc endopeptidases capable of digesting extracellular matrix components. The importance of MMPs in tumor development and invasion as well as other diseases is well known. MMP-3 (stromelysin-1, transin-1) has been shown to involved in tumor metastasis3 and rheumatoid arthritis. Therefore it is proposed as a therapeutic target for these diseases. The native pro-MMP-3 is Mr 59/57-kDa doublet, which can be autocatalyzed to an active form of 45-kDa, and is then processed partially to a second active form of 28-kDa.
Recombinant human MMP-3 enzyme was expressed as catalytic domain in E. coli. The molecular mass is 19.5 kDa. Purity is >95% by SDS-PAGE. Recombinant human MMP-3 catalytic domain doesn’t need APMA activation before enzyme assay. Its activity can be measured in FRET-based enzymatic assays.
Specifications
| Chemistry | |
| UniProt number |
|
|---|---|
| Molecular Mass/ Weight |
|
| Modification | |
| Conjugation |
|
| Quantity & Purity | |
| Concentration |
|
| Purity |
|
| Storage & stability | |
| Form |
|
| Storage Buffer |
|
| Storage Conditions |
|
| Activity | |
| Application | |
| Biomarker Target | |
| Unit definition |
|
| Specificity |
|
| Research Area | |
| Sub-category Research Area | |
| Usage |
|
| Source | |
| Host | |
| Source / Species |
|
Downloads
You may also be interested in the following product(s)
