Peptides

Hyaluronan Inhibitor - 1 mg

$107.00
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  • Cat.Number : AS-62622
  • Availability :
    In stock

Quantity

This 12 amino acids peptide is a hyaluronan inhibitor (HA), a high molecular weight glycosaminoglycan expressed abundantly in the extracellular matrix and on cell surfaces. This peptide shows specific binding to soluble, immobilized, and cell-associated forms of HA, and it inhibits leukocyte adhesion to HA substrates almost completely.

Specifications

Chemistry
Sequence one letter code
  • GAHWQFNALTVR
Sequence three letter code
  • H-Gly-Ala-His-Trp-Gln-Phe-Asn-Ala-Leu-Thr-Val-Arg-OH
Molecular Formula
  • C64H94N20O16
Molecular Mass/ Weight
  • 1399.7
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use

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Citations

TLR4 Is a Negative Regulator in Noninfectious Lung Inflammation.

J Immunol . 2010 Mar 31 ; 184(9) 5308 | DOI : 10.4049/jimmunol.1000009

  • H. Zhao

References

Development of a Peptide Inhibitor of Hyaluronan-Mediated Leukocyte Trafficking

J Exp Med . 2000 Sep 11 ; 192(6) 769 | DOI : https://doi.org/10.1084/jem.192.6.769

  • M. Mummert
  • et al