Peptides

IRAK-4 Peptide Substrate; IRAK-1 (360-380) - 1 mg

$172.00
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  • Cat.Number : AS-64959
  • Availability :
    In stock

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This is a substrate peptide for Interleukin-1 Receptor-Associated Kinase (IRAK) 4, derived from the IRAK-1 activation loop peptide amino acids 360 to 380. This peptide sequence contains Ser-376, one of the primary phospho-acceptor residues of IRAK-1. IRAK-4 phosphorylates IRAK-1 as a key step in regulation of inflammatory signaling pathways.

Specifications

Chemistry
Sequence one letter code
  • KKARFSRFAGSSPSQSSMVAR
Sequence three letter code
  • H-Lys-Lys-Ala-Arg-Phe-Ser-Arg-Phe-Ala-Gly-Ser-Ser-Pro-Ser-Gln-Ser-Ser-Met-Val-Ala-Arg-OH
Molecular Formula
  • C97H161N33O29S1
Molecular Mass/ Weight
  • 2285.7
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Application
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Human, monkey

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References

Steady-State Kinetic Characterization of Kinase Activity and Requirements for Mg2+ of Interleukin-1 Receptor-Associated Kinase-4

Biochem . 2010 Jan 27 ; 49(7) 1495 | DOI : https://doi.org/10.1021/bi901609m

  • M. Hekmat-Nejad
  • et al