IMG-EN-AS-64239-01.jpg
Peptides

JAG-1, Scrambled - 1 mg

$224.00
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  • Cat.Number : AS-64239
  • Availability :
    In production

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This peptide is a scrambled sequence of JAG-1 (188-204), a Notch Ligand

Specifications

Chemistry
Sequence one letter code
  • RCGPDCFDNYGRYKYCF
Sequence three letter code
  • H-Arg-Cys-Gly-Pro-Asp-Cys-Phe-Asp-Asn-Tyr-Gly-Arg-Tyr-Lys-Tyr-Cys-Phe-OH
Molecular Formula
  • C93H127N25O26S3
Molecular Mass/ Weight
  • 2107.5
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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JAG-1 (188-204), Jagged-1 (188-204), Notch Ligand, DSL Peptide - 1 mg

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Citations

Notch signaling activation is critical to the development of neuropathic pain

BMC Anesthesiol . 2015 Mar 28 ; 15 41 | DOI : 10.1186/s12871-015-0021-0

  • K. Xie

Activation of Notch signaling by short-term treatment with Jagged-1 enhances store-operated Ca(2+) entry in human pulmonary arterial smooth muscle cells.

Am J Physiol Cell Physiol . 2014 Feb 26 ; 306 C871 | DOI : 10.1152/ajpcell.00221.2013

  • H. Yamamura

References

Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-κB and PPARγ

Cell Death Different . 2002 Jul 16 ; 9(8) 842 | DOI : 10.1038/sj.cdd.4401036

  • B. Nickoloff
  • et al