Melan-A, MART-1 (27-35) - 1 mg
- Cat.Number : AS-60608
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Melan-A is a melanocyte differentiation antigen recognized by cytotoxic T lymphocytes. This sequence is a naturally presented Melan-A/MART-1 nonamer peptide. The Melan-A/MART-1 gene is expressed by normal melanocytes, as well as by most fresh melanoma samples and melanoma cell lines. This peptide appears to be a very common immunogenic epitope for HLA-A2-restricted melanoma-specific tumor-infiltrating lymphocytes (TIL) and may be useful for the development of immunotherapeutic strategies.
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References
Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes.
J Exp Med . 1994 Jul 01 ; 180(1) 347 | DOI : https://doi.org/10.1084/jem.180.1.347
- Y. Kawakami
- et al
Overlapping peptides of melanocyte differentiation antigen melan-A/MART-1 recognized by autologous cytolytic T lymphocytes in association with HLA-B45.1 and HLA-A2.1
Int J Cancer . 1998 Jan 30 ; 75(3) 451 | DOI : https://doi.org/10.1002/(SICI)1097-0215(19980130
- J. Schneider
- et al