IMG-EN-AS-62366-01.jpg
Peptides

Melittin, honey bee - 1 mg

$221.00
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  • Cat.Number : AS-62366
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    In stock

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Melittin, a 26-residue bee venom peptide, is known to induce murine antibodies specific for its hydrophilic C-terminus of residues 20 to 26 and T-cell responses specific for its hydrophobic mid-region (residue 11 to 19). This peptide is an anti-inflammatory agent, it inhibits the lyme disease spirochete.

Specifications

Chemistry
Sequence one letter code
  • GIGAVLKVLTTGLPALISWIKRKRQQ-NH2
Sequence three letter code
  • H-Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2
CAS registry number
  • 20449-79-0
Molecular Formula
  • C131H229N39O31
Molecular Mass/ Weight
  • 2846.7
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • honey bee

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Citations

Combination effects of antimicrobial peptides

Antimicrob Agents Chemother . 2016 Jan 04 ; 60(3) 1717 | DOI : 10.1128/AAC02434-15.

  • G. Yu

Alkylated dihydroxybenzoic acid as a MALDI matrix additive for hydrophobic peptide analysis.

Anal Chem . 2012 Apr 16 ; 84(9) 4237 | DOI : 10.1021/ac300540r

  • Y. Fukuyama

Covalent modification of a ten-residue cationic antimicrobial peptide with levofloxacin.

Front Chem . 2014 Sep 18 ; 2 71 | DOI : 10.3389/fchem.2014.00071

  • CA. Rodriguez

References

Structure-immunogenicity relationship of melittin, its transposed analogues, and D-melittin.

J. Immunol. . 1994 Aug 01 ; 153(3) 1124 | DOI : PubMed 8027544

  • T. King
  • et al

Structure and Orientation of the Pore-forming Peptide Melittin, in Lipid Bilayers

J. Mol. Biol. . 1994 Aug 18 ; 241(3) 456 | DOI : https://doi.org/10.1006/jmbi.1994.1520

  • R. Smith
  • et al