MOG (44-54), mouse, human, rat - 1 mg
- Cat.Number : AS-61620
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This 11mer peptide derived from myelin oligodendrocyte glycoprotein (MOG) (amino acids 44–54; conserved in human, mouse, rat) represents the core binding epitope for MOG-specific CD8+ T cells. This is the minimal, functionally constant, length of the MOG (35–55) peptide that binds to CD8+ MOG-specific T cells and stimulates T cell proliferation in vitro.
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References
Myelin oligodendrocyte glycoprotein peptide-induced experimental allergic encephalomyelitis and T cell responses are unaffected by immunoproteasome deficiency
J Neuroimmunol . 2007 Oct 26 ; 192(1-2) 124 | DOI : 10.1016/j.jneuroim.2007.09.024
- RF. Frausto
Encephalitogenic activity of truncated myelin oligodendrocyte glycoprotein (MOG) peptides and their recognition by CD8+ MOG‐specific T cells on oligomeric MHC class I molecules
Int Immunol . 2003 Jan 01 ; 15(2) 261 | DOI : https://doi.org/10.1093/intimm/dxg023
- D. Sun
- et al