SensoLyte® Anti-PLP (178-191) IgG Quantitative ELISA Kit (mouse) Colorimetric - 1 kit

Check your price
  • Cat.Number : AS-55523
  • Availability :
    In stock
  • Shipping conditions : Ice fees will apply

Alternative choices


Proteolipid protein (PLP) is the most abundant protein in the central nervous system (CNS) myelin sheath and is highly conserved among species. PLP has a 50% hydrophobic amino acids content and a molecular weight of 30 kDa. Mouse PLP (178-191) is able to induce autoantibody production and relapsing-remitting neurological disease causing extensive plaque-like demyelination. Autoantibody response to mouse PLP (171-191) has been observed in induced experimental autoimmune encephalomyelitis (EAE) in B10.PL, SJL, C57BL/6, F1, and BALB/c mice strains. However, the exact pathological role and action of anti-mouse PLP (178-191) autoantibody is not well understood.
The SensoLyte® Anti-PLP (178-191) IgG Quantitative ELISA Kit (mouse) provides a convenient and quantitative assay for anti-PLP (178-191) autoantibody in mouse. This kit is useful to researchers who want to determinine the amount of anti-PLP (178-191) antibody present in biological samples, and can help provide information on the role it plays in the development and treatment of EAE, an animal model for MS pathogenesis.


Kits components
  • Component A: PLP (178-191) coated and BSA blocked 8-well strips: 12 x 8 strips Component B: Mouse anti-PLP (178-191) IgG Standard: 100 µl (20 µg/ml) Component C: 1X Sample Dilution Buffer: 30 ml Component D: 10X Wash Buffer: 50 ml Component E: TMB color substrate solution: 10 ml Component F: Stop Solution: 10 ml Component G: Secondary antibody, Goat anti-Mouse IgG-HRP: 30 µl
UniProt number
  • P60202
Storage & stability
Storage Conditions
  • Store all other components at 4°C for up to 6 months. Store component B at -20°C in small aliquots. Protect components E and G from light.
Biomarker Target
Detection Method
Detection Limit
  • 100 pg
  • mouse
Research Area
Sub-category Research Area
  • Research use

You may also be interested in the following product(s)


MOG (35-55), mouse, rat

Cat.Number : AS-60130-1
$182.00 Excl. Tax

PLP (178-191) - 1 mg

Cat.Number : AS-62741
$119.00 Excl. Tax