SensoLyte® Anti-PLP (178-191) IgG Quantitative ELISA Kit (mouse) Colorimetric - 1 kit
- Cat.Number : AS-55523
- Manufacturer Ref. :
-
Availability :
In stock
- Shipping conditions : Ice fees will apply
Alternative choices
Proteolipid protein (PLP) is the most abundant protein in the central nervous system (CNS) myelin sheath and is highly conserved among species. PLP has a 50% hydrophobic amino acids content and a molecular weight of 30 kDa. Mouse PLP (178-191) is able to induce autoantibody production and relapsing-remitting neurological disease causing extensive plaque-like demyelination. Autoantibody response to mouse PLP (171-191) has been observed in induced experimental autoimmune encephalomyelitis (EAE) in B10.PL, SJL, C57BL/6, F1, and BALB/c mice strains. However, the exact pathological role and action of anti-mouse PLP (178-191) autoantibody is not well understood.
The SensoLyte® Anti-PLP (178-191) IgG Quantitative ELISA Kit (mouse) provides a convenient and quantitative assay for anti-PLP (178-191) autoantibody in mouse. This kit is useful to researchers who want to determinine the amount of anti-PLP (178-191) antibody present in biological samples, and can help provide information on the role it plays in the development and treatment of EAE, an animal model for MS pathogenesis.
Specifications
Packaging | |
Kits components |
|
---|---|
Chemistry | |
UniProt number |
|
Storage & stability | |
Storage Conditions |
|
Activity | |
Application | |
Biomarker Target | |
Detection Method | |
Detection Limit |
|
Specificity |
|
Research Area | |
Sub-category Research Area | |
Usage |
|
Downloads
You may also be interested in the following product(s)
![IMG-EN-AS-60130-1-01.jpg](/assets/cache/0b2fb224-0347-4a4f-a6e0-9ac6e6bdd983/500x500/as-60130-1-img-en-as-60130-1-01.jpg)
![IMG-EN-AS-62741-01.jpg](/assets/cache/ef114ae3-4687-4287-8ea9-86d052f80861/500x500/as-62741-img-en-as-62741-01.jpg)
![IMG-EN-AS-54465-01.jpg](/assets/cache/824cfea9-393c-4242-9470-6719b792f3d5/500x500/as-54465-img-en-as-54465-01.jpg)