MOG (92–106), mouse, rat - 1 mg
- Cat.Number : AS-62732
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This is amino acids 92 to 106 fragment of the myelin oligodendrocyte glycoprotein (MOG) from mouse/rat. Mice with MOG (92–106)-induced experimental autoimmune encephalomyelitis develop extensive B cell reactivity against secondary myelin antigens. Despite the fact that this MOG peptide induces only weak T cell responses, MOG-induced autoimmunity is very severe. This peptide is encephalitogenic in SJL mice, DA rats, and rhesus monkeys.
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References
A Structurally Available Encephalitogenic Epitope of Myelin Oligodendrocyte Glycoprotein Specifically Induces a Diversified Pathogenic Autoimmune Response
J Immunol . 2004 Jul 01 ; 173(1) 600 | DOI : https://doi.org/10.4049/jimmunol.173.1.600
- F. Bischof
- et al