IMG-EN-AS-60323-5-01.jpg
Peptides

Proteases Substrate, Fluorogenic, (Z-R)2Rh110•2HCl - 5 mg

$143.00
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  • Cat.Number : AS-60323-5
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(Z-Arg)2Rh110 is a generic fluorogenic substrate for proteases such as trypsin, cathepsin B and L. The colorless (Z-Arg)2Rh110 is hydrolyzed to highly fluorescent rhodamine 110, which exhibits excellent spectral properties that match the optimal detection window of most fluorescence instruments. Abs/Em = 501/527 nm

Specifications

Chemistry
Sequence one letter code
  • (Z-R)2Rh110•2HCl
Sequence three letter code
  • (Z-Arg)2Rh110 • 2HCl
Molecular Mass/ Weight
  • 910.9•73.0
Properties
Absorbance (nm)
  • 501
Emission (nm)
  • 527
Modification
Conjugation type
  • Fluorescent dyes
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • -20°C Protected from Light
Activity
Application
Biomarker Target
Detection Method
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Synthetic construct

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References

Detection of lysosomal cysteine proteinases in microglia: flow cytometric measurement and histochemical localization of cathepsin B and L

Glia . 1993 Feb 01 ; 7(2) 183 | DOI : https://doi.org/10.1002/glia.440070208

  • RB Banati,
  • et al

Flow cytometric analysis of protease activities in vital cells.

Biol Chem . 2009 Oct 16 ; 373(2) 547 | DOI : https://doi.org/10.1515/bchm3.1992.373.2.547

  • G. Rothe
  • et al

Trypsinogen activation in rat pancreatic acinar cells hyperstimulated by caerulein.

Biochim Biophys Acta . 1997 Dec 31 ; 1362(2-3) 243 | DOI : https://doi.org/10.1016/S0925-4439(97)00082-3

  • W. Halangk
  • et al