IMG-EN-AS-60463-1-01.jpg
Peptides

Renin Inhibitor Peptide, WFML Peptide, rat - 1 mg

$221.00
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  • Cat.Number : AS-60463-1
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    In stock

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A specific rat renin inhibitor.

Specifications

Chemistry
Sequence one letter code
  • Ac-HPFV-(Sta)-LF-NH2
Sequence three letter code
  • Ac-His-Pro-Phe-Val-Sta-Leu-Phe-NH2
Molecular Formula
  • C51H74N10O9
Molecular Mass/ Weight
  • 957.3
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Application
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • rat

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Citations

COX-2 mediates angiotensin II-induced (pro) renin receptor expression in the rat renal medulla.

Am J Physiol Renal Physiol. . 2014 Apr 16 ; 307(1) F25 | DOI : 10.1152/ajprenal.00548.2013

  • F. Wang

Renin released from mast cells activated by circulating MCP-1 initiates the microvascular phase of the systemic inflammation of alveolar hypoxia

Am J Physiol Heart Circ Physiol . 2011 Sep 30 ; 301(6) H2264 | DOI : 10.1152/ajpheart.00461.2011

  • J. Chao

Soluble Form of the (Pro)Renin Receptor Is Augmented in the Collecting Duct and Urine of Chronic Angiotensin II–Dependent Hypertensive Rats.

Hypertension . 2011 Feb 14 ; 57(4) 859 | DOI : 10.1161/HYPERTENSIONAHA.110.167957

  • A. Gonzalez

Angiotensin II stimulates Renin in inner medullary collecting duct cells via Protein Kinase C and independent of epithelial Sodium channel and mineralocorticoid receptor activity

Hypertension . 2011 Jan 31 ; 57(3) 594 | DOI : 10.1161/HYPERTENSIONAHA.110.165902

  • A. Gonzalez

Increased renin excretion is associated with augmented urinary angiotensin II levels in chronic angiotensin II-infused hypertensive rats

Am J Physiol Renal Physiol. . 2011 Aug 24 ; 301(6) F1195 | DOI : 10.1152/ajprenal.00339.2011

  • L. Liu

Characterization of the genomic structure and function of regions influencing renin and angiogenesis in the SS rat

Physiol Genomics . 2011 Apr 26 ; 43(13) 808 | DOI : 10.1152/physiolgenomics.00171.2010

  • T. Stodola

Cardiovascular interactions between losartan and fructose in mice

J Cardiovasc Pharmacol Ther . 2012 Apr 10 ; 15(1) 68 | DOI : 10.1177/1074248409351409

  • D. Senador

Angiotensin-(1-12) is an alternate substrate for angiotensin peptide production in the heart.

Am J Physiol Heart Circ Physiol. . 2008 Mar 21 ; 294(5) 294(5) | DOI : 10.1152/ajpheart.00175.2008

  • A. Trask

Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2

Circulation . 2005 May 16 ; 111(20) 2605 | DOI : 10.1161/CIRCULATIONAHA.104.510461

  • CM. Ferrario

Effects of renin-angiotensin system blockade on renal angiotensin-(1-7) forming enzymes and receptors

Kidney Int. . 2005 Nov 01 ; 68(5) 2189 | DOI : 10.1111/j.1523-1755.2005.00675.x

  • CM. Ferrario

Angiotensin receptors contribute to blood pressure homeostasis in salt-depleted SHR.

Am J Physiol Regul Integr Comp Physiol. . 2003 Jan 01 ; 284(1) R164 | DOI : 10.1152/ajpregu.00210.2002

  • S. Nakamura

References

Role of AT1 and AT2 Receptors in the Plasma Clearance of Angiotensin II

J. Cardiovasc. Pharmacol. . 1998 Mar 01 ; 31(3) 464 | DOI : 10.1097/00005344-199803000-00019

  • SN. Iyer
  • et al