Peptides
S3 Fragment, ADF/cofilin, LIMK1 substrate - 1 mg
$133.00
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- Cat.Number : AS-62637
- Manufacturer Ref. :
-
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This peptide contains the unique amino-terminal phosphorylation site of Xenopus ADF/cofilin, the LIM kinase (LIMK) phosphorylation site. LIMK1 is a key regulator of the actin cytoskeleton through its phosphorylation of ADF/cofilin at serine-3 for inactivation. This peptide is a fragment of the S3 peptide containing the serine-3 sequence of ADF/cofilin that has been widely used as an effective competitive inhibitor of LIMK1.
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References
BMP gradients steer nerve growth cones by a balancing act of LIM kinase and Slingshot phosphatase on ADF/cofilin
J Cell Biol . 2007 Jul 02 ; 178(1) 107 | DOI : https://doi.org/10.1083/jcb.200703055
- Z. Wen
- et al