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Peptides

SHLP6 (Small humanin-like peptide 6) - 1 mg

$370.00
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  • Cat.Number : AS-65591
  • Availability :
    In stock

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Recent advances in high-resolution sequencing have led to the discovery of unique peptides derived from mitochondrial genome.1-2Currently 8 peptides are identified: humanin, mitochondrial open reading frame of the 12S tRNA-c (MOTS-c), and six small humanin-like peptides (SHLP1-6). 1-2All of these peptides are released into cytosol from mitochondria. SHLP6 has been shown to increase apoptosis with potential cancer targeting roles and also may be involved in aging.1-2

Specifications

Chemistry
Sequence one letter code
  • H - MLDQDIPMVQPLLKVRLFND - OH
Sequence three letter code
  • NH2-Met-Leu-Asp-Gln-Asp-Ile-Pro-Met-Val-Gln-Pro-Leu-Leu-Lys-Val-Arg-Leu-Phe-Asn-Asp-COOH
Molecular Mass/ Weight
  • 2386
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

The Mitochondrial-Derived Peptides, HumaninS14G and Small Humanin-like Peptide 2, Exhibit Chaperone-like Activity

Sci Reports . 2017 Aug 10 ; 7(7802) 1 | DOI : https://doi.org/10.1038/s41598-017-08372-5

  • A.K. Okada
  • et al

The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance

Cell Met . 2015 Mar 03 ; 21(3) 443 | DOI : https://doi.org/10.1016/j.cmet.2015.02.009

  • C. Lee
  • et al

Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers

AGING . 2016 Apr 10 ; 8(4) 796 | DOI : 10.18632/aging.100943

  • L.J. Cobb
  • et al