Somatostatin 14, human, rat, mouse, pig, chicken, frog

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  • Cat.Number : AS-24277
  • Availability :
    In stock


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Somatostatin [SST, GHIH (growth hormone-inhibiting hormone) or SRIF (somatotropin release-inhibiting factor)] is a cyclic peptide hormone existing as two isoforms and produced in the pancreas islet, GI tract and the central nervous system. Tetradecapeptide Somatostatin-14 (SRIF-14, the originally identified somatostatin) and the 28-amino acid Somatostatin-28 (SRIF-28) have similar biological activities but differ in their potency. Somatostatins regulate the endocrine system: they inhibit the release of growth hormone in contrast to Growth Hormone Factor (GRF), which stimulates the release of growth hormone. They also inhibit the release of prolactin and thyrotropin, peptide hormones from the pituitary gland and glucagon and insulin from the pancreas. They control the secretion of gut hormones and function as neurotransmitters.


Sequence one letter code
  • AGCKNFFWKTFTSC (Disulfide bridge: 3-14)
Sequence three letter code
  • H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (Disulfide bridge: 3-14)
CAS registry number
  • 38916-34-6
Molecular Formula
  • C76H104N18O19S2
Molecular Mass/ Weight
  • 1638
  • Unconjugated
Quantity & Purity
  • Peak Area by HPLC ≥95%
Storage & stability
  • Lyophilized
Storage Conditions
  • - 20 °C
Biomarker Target
Research Area
Sub-category Research Area
  • Research use
Source / Species
  • human, rat, mouse, pig, chicken, frog

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The use of acetone as a substitute for acetonitrile in analysis of peptides by liquid chromatography/electrospray ionization mass spectrometry.

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  • D. Kim
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  • W. Meyerhof
  • et al