Peptides

Steroid Receptor Coactivator-1 (SRC-1), (676-700), biotin labeled - 1 mg

$261.00
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  • Cat.Number : AS-62152
  • Availability :
    In stock

Quantity

This is amino acids 676 to 700 fragment of steroid receptor co-activator (SRC1). This N-terminal biotinylated peptide is derived from the second LXXLL motif of SRC1. Co-activator proteins interact with nuclear receptors in a ligand-dependent manner and augment transcription. A short amphipathic beta-helical domain that includes this LXXLL motif serves as the interaction interface between the co-activator molecules and the ligand-dependent activation function (AF-2) located in the COOH-terminus of the nuclear receptor ligand-binding domain (LBD). Receptor binding domain of the co-activator SRC-1 is specifically recruited to the farnesoid X receptor (FXR) ligand-binding domain.

Specifications

Chemistry
Sequence one letter code
  • Biotin-CPSSHSSLTERHKILHRLLQEGSPS
Sequence three letter code
  • Biotin-Cys-Pro-Ser-Ser-His-Ser-Ser-Leu-Thr-Glu-Arg-His-Lys-Ile-Leu-His-Arg-Leu-Leu-Gln-Glu-Gly-Ser-Pro-Ser-OH
Molecular Formula
  • C128H209N41O40S2
Molecular Mass/ Weight
  • 3026.6
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Human, pig, mouse, bovine

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