Peptides

Steroid Receptor Coactivator-1, SRC-1 (686-700) - 1 mg

$110.00
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  • Cat.Number : AS-64661
  • Availability :
    In stock

Quantity

This peptide is amino acids 686 to 700 fragment containing the second LXXLL motif, derived from NR box II of steroid receptor coactivator (SRC1). Coactivator proteins interact with nuclear receptors in a ligand-dependent manner and augment transcription.

Specifications

Chemistry
Sequence one letter code
  • RHKILHRLLQEGSPS
Sequence three letter code
  • H-Arg-His-Lys-Ile-Leu-His-Arg-Leu-Leu-Gln-Glu-Gly-Ser-Pro-Ser-OH
Molecular Formula
  • C77H131N27O21
Molecular Mass/ Weight
  • 1771.2
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Human, pig, mouse, bovine, rat

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References

A Natural Product That Lowers Cholesterol As an Antagonist Ligand for FXR

Science . 2002 Mar 02 ; 296(5573) 1703 | DOI : 10.1126/science.1072891

  • N. Urizar
  • et al

Bile Acids: Natural Ligands for an Orphan Nuclear Receptor

Science . 1999 May 21 ; 284(5418) 1365 | DOI : 10.1126/science.284.5418.1365

  • D. Parks
  • et al