IMG-EN-AS-22552-01.jpg
Peptides

Syntide-2 [PLARTLSVAGLPGKK] - 5 mg

$248.00
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  • Cat.Number : AS-22552
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The native peptide PLARTLSVAGLPGKK is a selective substrate for CaM kinase II and protein kinase C. It is a poor substrate for phosphorylase kinase and is not phosphorylated by myosin light chain kinase. The sequence of PLARTLSVAGLPGKK is homologous to phosphorylation site 2 in glycogen synthase. The relative Vmax/Km ratios of the peptide for different kinases are 100 for CaMK II, 22 for protein kinase C, 2 for phosphorylase kinase, and 0.5 for myosin light chain kinase respectively.

Specifications

Chemistry
Sequence one letter code
  • PLARTLSVAGLPGKK
Sequence three letter code
  • H-Pro-Leu-Ala-Arg-Thr-Leu-Ser-Val-Ala-Gly-Leu-Pro-Gly-Lys-Lys-OH
CAS registry number
  • 108334-68-5
Molecular Formula
  • C68H122N20O18
Molecular Mass/ Weight
  • 1507.9
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Application
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use

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References

Calcium · calmodulin-dependent protein kinase II and calcium · phospholipid-dependent protein kinase activities in rat tissues assayed with a synthetic peptide

Arch Biochem Biophys . 1987 Feb 01 ; 252(2) 252 | DOI : https://doi.org/10.1016/0003-9861(87)90048-8

  • H. Hashimoto
  • TR. Soderling

CaM kinase II-alpha activity, levels and Ca/calmodulin dependent phosphorylation of substrate proteins in mice brain during fatal murine cerebral malaria

Neurosci Lett . 2003 Jan 16 ; 336(2) 121 | DOI : https://doi.org/10.1016/S0304-3940(02)01100-X

  • KA. Kumar
  • PP. Babu

Purification and Characterization of a Novel Protein Activator of Ca2+/Calmodulin-Dependent Protein Kinase I

Biochem Biophys Res Commun . 1994 Oct 24 ; 215(3) 861 | DOI : https://doi.org/10.1006/bbrc.1995.2543

  • S. Inoue
  • et al