IMG-EN-AS-61992-01.jpg
Peptides

TIF2 (740-753), Transcriptional Intermediary Factor 2 - 1 mg

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  • Cat.Number : AS-61992
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This peptide is a nuclear receptor (NR) box B3 region of the p160 co-activator Transcriptional Intermediary Factor 2 (TIF2) peptide, a LXXLL motif. The activation function 2/ligand-dependent interaction between nuclear receptors and their co-regulators is mediated by a short consensus motif nuclear receptor box.

Specifications

Chemistry
Sequence one letter code
  • KENALLRYLLDKDD
Sequence three letter code
  • H-Lys-Glu-Asn-Ala-Leu-Leu-Arg-Tyr-Leu-Leu-Asp-Lys-Asp-Asp-OH
Molecular Formula
  • C75H124N20O25
Molecular Mass/ Weight
  • 1706
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Human, mouse, rat

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Citations

Agonist versus antagonist induce distinct thermodynamic modes of co-factor binding to the glucocorticoid receptor

Biophys Chem.  . 2007 Apr 05 ; 128(2-3) 156 | DOI : 10.1016/j.bpc.2007.03.013

  • R. Kroe

References

Interaction of Transcriptional Intermediary Factor 2 Nuclear Receptor Box Peptides with the Coactivator Binding Site of Estrogen Receptor

J Biol Chem . 2002 Jun 01 ; 277(24) 21862 | DOI : https://doi.org/10.1074/jbc.M200764200

  • A. Wärnmark
  • et al