Existing Account

Please login first to complete purchase/ quotation request, view custom order reports, or create favorites list.

Customer ID:
Stay Logged In

Forgot your Customer ID or Password?
New Account

Don't have an account with us yet? Please set up an account to place order or obtain customer services.

Fluorescent Dyes  >  Enzyme Detection Reagents  >>  Dihydroethidium

Product Name Dihydroethidium
[Hydroethidine] *Special Air - free Packaging*
Size 10 mg
Catalog # AS-85717
US$ $193

Generic substrate for fluorimetric detection of oxidases (including peroxidase); The oxidized product tends to accumulate in nuclei.

Store at -20C desiccated and protected from light.

Kit size: 10 x 1 mg

Detailed Information Material Safety Data Sheets (MSDS)
References Donato MT, et al. (2004). Fluorescence-based assays for screening nine cytochrome P450 (P450) activities in intact cells expressing individual human P450 enzymes. Drug Metab Dispos 32, 699-706, Liu J, et al. (2004). The effect of reciprocal active site mutations in human cytochromes P450 1A1 and 1A2 on alkoxyresorufin metabolism. Arch Biochem Biophys 424, 33-43, Chougnet A, et al. (2003). Design and synthesis of a new fluorescent probe for cytochrome P450 3A4 (CYP 3A4). Bioorg Med Chem Lett 13, 3643-5, Dunn AR, et al. (2002). Fluorescent probes for cytochrome P450 structural characterization and inhibitor screening. J Am Chem Soc 124, 10254-5, Nakamura K, et al. (2001). Coumarin substrates for cytochrome P450 2D6 fluorescence assays. Anal Biochem 292, 280-6, Thapliyal R and Maru GB (2001). Inhibition of cytochrome P450 isozymes by curcumins in vitro and in vivo. Food Chem Toxicol 39, 541-7, Roser R and Thomas H (2000). A direct, highly sensitive fluorimetric assay for a microsomal cytochrome P450-mediated O-demethylation using a novel coumarin analog as substrate. Z Naturforsch [C] 55, 915-22, Kobayashi Y, et al. (1998). Probing the active site of cytochrome P450 2B1: metabolism of 7-alkoxycoumarins by the wild type and five site-directed mutants. Biochemistry 37, 6679-88.
Molecular Weight 315.42
Spectral Properties Abs/Em = 518/605 nm (after oxidation)
Solvent System DMSO
Product Citations Seidler, E. et al. (2010). Effectiveness of Novel Borane−Phosphine Complexes in Inhibiting Cell Death Depends on the Source of Superoxide Production Induced by Blockade of Mitochondrial Electron Transport. ACS Chem Neurosci 1, 95.
  < Back