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Peptides  >  NF-kB/Transcription Factors Related Peptides   >>  PTD-p65-P1 Peptide

Product Name PTD - p65 - P1 Peptide
DRQIKIWFQNRRMKWKKQLRRPSDRELSE
Size 1 mg
Catalog # 61168
US$ $231
Purity % Peak Area By HPLC ≥ 95%
Description

This is a membrane-translocating peptide sequence derived from antennapedia (PTD) conjugated with p65-P1. It suppresses NF-kB activation induced by lipopolysaccharide, interleukin-1, okadaic acid, phorbol 12-myristate 13-acetate, and H2O2. This peptide may play a role in sensitizing cells to apoptosis induced by TNF, doxorubicin, and cisplatin. p65-P1 contains a single phosphorylation site, and it is needed to inhibit NF-B activity.

Detailed Information Datasheet
Storage -20C
References Ref: Takada, Y. et al. J. Biol. Chem. 279, 15096 (2004).
Molecular Weight 3829.5
Sequence
(One-Letter Code)
DRQIKIWFQNRRMKWKKQLRRPSDRELSE
Sequence
(Three-Letter Code)
H - Asp - Arg - Gln - Ile - Lys - Ile - Trp - Phe - Gln - Asn - Arg - Arg - Met - Lys - Trp - Lys - Lys - Gln - Leu - Arg - Arg - Pro - Ser - Asp - Arg - Glu - Leu - Ser - Glu - OH
     
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