This is a the tandem repeat sequence of the MUC1 mucin core. MUC1 is a high molecular weight glycoprotein over-expressed by adenocarcinomas, and by different types of bladder tumors. It is also expressed by normal human epithelial cells.
Ref: Schuman, J. et al. Biopolymers 77, 107 (2005); Petrakou et al. Tumor Biol. 19, 21 (1998); Apostolopoulos, V. et al. Frontiers Biosci. 6, d1311 (2001); Murray, A. et al. J. Nucl. Med. 42, 726 (2001); Agrawal, B. and B. Longenecker, Intl. Immunol. 17, 391 (2005).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Ala - Pro - Asp - Thr - Arg - Pro - Ala - Pro - Gly - OH