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Peptides > Peptidoglycan Peptides >> Ala-γ-D-Glu-DAP

Product Name	Ala - γ - D - Glu - DAP A - (γ - e) - DAP
Size	1 mg
Catalog #	AS-60774
US$	$181
Purity	% Peak Area By HPLC ≥ 95%
Description	This peptide, with the diaminopimelic acid coupled to the γ-carboxylic acid of the D-isomer of Glu, stimulates Nod1-dependent apoptosis.
Detailed Information	Datasheet
Storage	-20°C
References	da Silva Correia, J. et al. Proc. Natl. Acad. Sci. USA 103, 1840 (2006); Baum, EZ. et al. Antimicrobial Agents Chemo. 50, 230 (2006).
Molecular Weight	390.4
Sequence (One-Letter Code)	A-(γ-e)-DAP
Sequence (Three-Letter Code)	H - Ala - D - γ - Glu - diaminopimelic acid
Product Citations	Seshadri, S. et al. (2009). MAIL regulates human monocyte IL-6 production. J Immunol 183, 5358. Fukazawa, A. et al. (2008). GEF-H1 mediated control of NOD1 dependent NF-κB activation by Shigella effectors. PLoS Pathog 4, e1000228. Swaan, PW. et al. (2008). Bacterial peptide recognition and immune activation facilitated by human peptide transporter PEPT2. Am J Respir Cell Mol Biol 39, 536. da Silva Correia, J. et al. (2007). The subunit CSN6 of the COP9 signalosome is cleaved during apoptosis. J Biol Chem 282, 12557. da Silva Correia, J. et al. (2007). SGT1 is essential for Nod1activation Proc Natl Acad Sci 104, 6764.

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