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Peptides  >  Signal Transduction Peptides  >>  TIF2 (740-753), Transcriptional Intermediary Factor 2 (740-753)
Product Name TIF2 (740 - 753), Transcriptional Intermediary Factor 2 (740 - 753)
Size 1 mg
Catalog # 61992
US$ $93
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide is a nuclear receptor (NR) box B3 region of the p160 co-activator Transcriptional Intermediary Factor 2 (TIF2) peptide, a LXXLL motif. The activation function 2/ligand-dependent interaction between nuclear receptors and their co-regulators is mediated by a short consensus motif nuclear receptor box.
Detailed Information Datasheet
Storage -20°C
References Wärnmark, A., et al. J. Biol. Chem. 277, 21862 (2002).
Molecular Weight 1705.9
Sequence
(One-Letter Code)		 KENALLRYLLDKDD
Sequence
(Three-Letter Code)		 H - Lys - Glu - Asn - Ala - Leu - Leu - Arg - Tyr - Leu - Leu - Asp - Lys - Asp - Asp - OH
Product Citations Kroe, R. et al. (2007). Agonist versus antagonist induce distinct thermodynamic modes of co-factor binding to the glucocorticoid receptor. Biophys Chem 128, 156.
     
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