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Peptides  >  OVA Peptides  >>  E1, (E257)

Product Name E1, (E257)
EIINFEKL
Size 1 mg
Catalog # 62194
US$ $71
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide is an antagonist variant of OVA (257-264). It induces positive selection on the beta 2M (-/-), and negative selection on beta 2M (+/-) background. This peptide was used to study the ability of the wild-type or mutant TCRs to transduce signals leading to positive or negative selection, and was utilized in several thymocyte development studies. E1 presentation leads to Egr-1 induction and ERK phosphorylation.

Detailed Information Datasheet
Storage -20°C
References Canté-Barrett, K. et al. J. Immunol. 176, 2299 (2006); Worlen, G. et al. Nature 406, 422 (2000); Starr, T. et al. J. Immunol. 171, 4512 (2003).
Molecular Weight 1005.2
Sequence
(One-Letter Code)
EIINFEKL
Sequence
(Three-Letter Code)
H - Glu - Ile - Ile - Asn - Phe - Glu - Lys - Leu - OH
Product Citations Canté-Barrett, K. et al. J. Immunol. 176, 2299 (2006).
     
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