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Peptides  >  Cell Adhesion Peptides  >>  40Gap 27, Connexin Mimetic

Product Name 40Gap 27, Connexin Mimetic
Size 1 mg
Catalog # AS-62641
US$ $77
Purity % Peak Area By HPLC ≥ 95%

This peptide corresponds to the GAP27 domain of the second extracellular loop of dominant vascular connexin (Cx40), designated as 40Gap 27. It was used to investigate mechanisms through which oxidant stress impairs communication via gap junctions. When administered, 40Gap27attenuates endothelium-dependent subintimal smooth muscle hyperpolarization.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C
References Chaytor, A. et al. British J. Pharmacol. 144, 108 (2005).
Molecular Weight 1289.5
(One-Letter Code)
(Three-Letter Code)
H - Ser - Arg - Pro - Thr - Glu - Lys - Asn - Val - Phe - Ile - Val - OH
Product Citations Yi, FX. et al. (2010). Pregnancy Enhances Sustained Ca2+ Bursts and Endothelial Nitric Oxide Synthase Activation in Ovine Uterine Artery Endothelial Cells Through Increased Connexin 43 Function. Biol Reprod 82, 66.
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