40Gap 27, Connexin Mimetic - 1 mg
- Cat.Number : AS-62641
- Manufacturer Ref. :
-
Availability :
In stock
This peptide corresponds to the GAP27 domain of the second extracellular loop of dominant vascular connexin (Cx40), designated as 40Gap 27. It was used to investigate mechanisms through which oxidant stress impairs communication via gap junctions. When administered, 40Gap27attenuates endothelium-dependent subintimal smooth muscle hyperpolarization.
Specifications
| Chemistry | |
| Sequence one letter code |
|
|---|---|
| Sequence three letter code |
|
| Molecular Formula |
|
| Molecular Mass/ Weight |
|
| Modification | |
| Conjugation |
|
| Quantity & Purity | |
| Purity |
|
| Storage & stability | |
| Form |
|
| Storage Conditions |
|
| Activity | |
| Biomarker Target | |
| Research Area | |
| Sub-category Research Area | |
| Usage |
|
| Source | |
| Source / Species |
|
Downloads
You may also be interested in the following product(s)
43Gap 27, Connexin (200-210) (human, mouse, rat) scrambled - 1 mg
Citations
Pregnancy Enhances Sustained Ca2+ Bursts and Endothelial Nitric Oxide Synthase Activation in Ovine Uterine Artery Endothelial Cells Through Increased Connexin 43 Function.
Biol Reprod . 2009 Sep 09 ; 82(1) 66 | DOI : 10.1095/biolreprod.109.078253
- FX. Yi
The FGF-2-triggered protection of cardiac subsarcolemmal mitochondria from calcium overload is mitochondrial connexin 43-dependent.
Cardio Res . 2014 Mar 20 ; 103(1) 72 | DOI : 10.1093/cvr/cvu066.
- W. Srisakuldee
References
Connexin-mimetic peptides dissociate electrotonic EDHF-type signalling via myoendothelial and smooth muscle gap junctions in the rabbit iliac artery
British J Pharmacol . 2005 Jan 29 ; 144(1) 108 | DOI : https://doi.org/10.1038/sj.bjp.0706046
- A. Chaytor
- et al