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Peptides  >  Protein Phosphorylation Related Peptides  >>  Cathepsin K substrate

Product Name Cathepsin K substrate
Abz - HPGGPQ - EDDnp
Size 0.1 mg
Catalog # 62368
US$ $115
Purity % Peak Area By HPLC ≥ 95%
Description

This FRET peptide can be used to monitor selectively cathepsin K activity in physiological fluids and cell lysates. Abz-HPGGPQ-EDDnp [where Abz represents o-aminobenzoic acid and EDDnp represents N -(2,4-dinitrophenyl)-ethylenediamine], a substrate initially developed for trypanosomal enzymes, is efficiently cleaved at the Gly-Gly bond by cathepsin K. This peptide is resistant to hydrolysis by cathepsins B, F, H, L, S and V, Ex/Em=340 nm/420 nm.

Storage -20C
References Lecaille, F. et al. Biochem. J. 375, 307(2003).
Molecular Weight 920
Sequence
(One-Letter Code)
Abz-HPGGPQ-EDDnp
Sequence
(Three-Letter Code)
Abz - His - Pro - Gly - Gly - Pro - Gln - EDDnp
     
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