IMG-EN-AS-63693-01.jpg
Peptides

LC-LL-37, biotinylated - 0.5 mg

$364.00
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  • Cat.Number : AS-63693
  • Availability :
    In stock

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Antimicrobial peptide LL-37, belonging to the cathelicidin family, is the first amphipathic alpha-helical peptide isolated from human. It plays an important role in the first line of defense (innate immunity) against local infection and systemic invasion of pathogens at sites of inflammation and wounds. This peptide is biotinylated.

Specifications

Chemistry
Sequence one letter code
  • Biotin-LC-LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES
Sequence three letter code
  • Biotin-LC-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH
Molecular Mass/ Weight
  • 4833
Modification
Conjugation type
  • Biotins
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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Citations

Acyl carrier protein is a bacterial cytoplasmic target of cationic antimicrobial peptide LL-37

Biochem J . 2015 Jul 17 ; 470(2) 243 | DOI : 10.1042/BJ20150432.

  • MC. Chung

Chlamydial plasmid-encoded virulence factor Pgp3 neutralizes the antichlamydial activity of human cathelicidin LL-37

Infect Immun . 2015 Sep 28 ; 83(12) 4701 | DOI : 10.1128/IAI.00746-15

  • S. Hou