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Peptides  >  Kinases/Phosphatase Substrates  >  Insulin Receptor Tyrosine Kinase  >>  IGF-IRtide

Product Name IGF - IRtide
Size 1 mg
Catalog # AS-61265
US$ $176
Purity % Peak Area By HPLC ≥ 95%

This is a synthetic substrate for insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase domain with a low Km (263.9M) for binding. This peptide sequence is based on the position of tyrosine in the sequence (phosphorylation site: Y895) of Insulin receptor substrate-1 (IRS-1) protein. The YVNI site within the sequence is important for binding to SH2 domains.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C
References 1, Xu B. et al. J Biol Chem, 270(50):29825 (1995).
2, Favelyukis S. et al. Nat Struct Biol. 8:1058 (2001)
Molecular Weight 1595.8
(One-Letter Code)
(Three-Letter Code)
H - Lys - Lys - Lys - Ser - Pro - Gly - Glu - Tyr - Val - Asn - Ile - Glu - Phe - Gly - OH
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