This is a peptide substrate that is phosphorylated by Serine/Threonine kinase 11 (STK11), also known as LKB1. LKBtide is derived from sucrose non-fermenting 1 (SNF1) protein kinase, which is normally activated by the LKB1/AMP-activated protein kinase (AMPK) signaling pathway.
Branvold, DJ. et al. J Appl Physiol105, 1288 (2008).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Leu - Ser - Asn - Leu - Tyr - His - Gln - Gly - Lys - Phe - Leu - Gln - Thr - Phe - Cys - Gly - Ser - Pro - Leu - Tyr - Arg - Arg - Arg - OH