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Peptides  >  Histones  >  Histone H4 Peptides  >>  [Lys(Ac)12]-Histone H4 (1-21)-GGK(Biotin), H4K12(Ac), biotin-labeled

Product Name [Lys(Ac)12] - Histone H4 (1 - 21) - GGK(Biotin), H4K12(Ac), biotin - labeled
Size 0.25 mg
Catalog # AS-64849-025
US$ $127
Purity % Peak Area By HPLC ≥ 95%

This peptide is histone H4 (1-21), acetylated at lysine 12. The N-terminus contains a C-terminus GG linker followed by a biotinylated lysine. The acetylation of histone H4 plays a crucial role in structural changes that amplifies the binding of transcription factors to their recognition sites within the nucleosomes. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.

Storage -20C
References Vettes-Dadey, M. et al. Embo J 15, 10 (1996).
Molecular Weight 2644.1
(One-Letter Code)
(Three-Letter Code)
Ac - Ser - Gly - Arg - Gly - Lys - Gly - Gly - Lys - Gly - Leu - Gly - Lys(Ac) - Gly - Gly - Ala - Lys - Arg - His - Arg - Lys - Val - Gly - Gly - Lys(Biotin) - OH
Product Citations Adhikary, S. et al. (2015). Selective recognition of H3.1K36 dimethylation/H4K16 acetylation facilitates the regulation of all-trans-retinoic acid (ATRA)-responsive genes by putative chromatin reader ZMYND8 J. Biol. Chem. 291 2664-2681 doi: 10.1074/jbc.M115.679985
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