Peptides

Proadrenomedullin N-term peptide, PAMP (1-20) - 5 mg

$245.00
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  • Cat.Number : AS-65455-5
  • Availability :
    In stock

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PAMP (1-20) is a biologically active molecule produced by posttranslational processing of proadrenomedullin. This peptide is found in a variety of tissues and exerts important biological activities through specific cell surface receptors. PAMP (1-20) is involved in many physiological processes, including vasodilation, bronchodilation, hormone secretion, cell migration, apoptosis, and angiogenesis. This peptide has been implicated in the pathophysiology of several diseases such as renal and cardiovascular disorders, stroke, cancer, and diabetes.

Specifications

Chemistry
Sequence one letter code
  • ARLDVASEFRKKWNKWALSR-NH2
Sequence three letter code
  • H-Ala-Arg-Leu-Asp-Val-Ala-Ser-Glu-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-NH3
CAS registry number
  • 150238-87-2
Molecular Formula
  • C112H178N36O27
Molecular Mass/ Weight
  • 2461
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

Identification of MrgX2 as a human G-protein-coupled receptor for proadrenomedullin N-terminal peptides

Biochem Biophys Res Commun . 2005 May 20 ; 330(4) 1146 | DOI : https://doi.org/10.1016/j.bbrc.2005.03.088

  • M. Kamohara
  • et al

Proadrenomedullin N-Terminal 20 Peptide

Hypertension . 1998 Nov 01 ; 32 907 | DOI : https://doi.org/10.1161/01.HYP.32.5.907

  • M. Mahata
  • et al