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Peptides  >  Apoptosis Peptides  >>  Caspase 3 (Apopain) Inhibitor 1

Product Name Caspase 3 (Apopain) Inhibitor 1
Size 5 mg
Catalog # AS-25269-5
US$ $231
Purity % Peak Area By HPLC ≥ 95%

This is an acetylated tetrapeptide aldehyde (caspase 3) inhibitor peptide. It is observed to cause complete inhibition when apopain protease is set to cleave PARP. Ac-DEVD-CHO at a concentration of 120 M was found to inhibit Fas-induced apoptosis in Jurkat T cells.

Detailed Information Datasheet
Storage -20C
References 1, Schlel J. et al. J Biol Chem 271(4):18411844 (1996)
2, Nicholson D. et al. Nature 376, 37 (1995)
3, Enari M. et al. Nature 380, 723 (1996).
Molecular Weight 502.5
(One-Letter Code)
(Three-Letter Code)
Ac - Asp - Glu - Val - Asp - CHO
Product Citations Ghosh, S. et al. (2009). Moderate exercise attenuates caspase-3 activity, oxidative stress, and inhibits progression of diabetic renal disease in db/db mice. Am J Physiol Renal Physiol2964:F700-810. doi: 10.1152/ajprenal.90548.

Gylys, KH. et al. (2004). Rapid annexin-V labeling in synaptosomes. Neurochem. Intl.443: 125-131. doi: 10.1016/S0197-0186(03)00146-3.

Naqvi, T. et al. (2004). Galactosidase enzyme fragment complementation as a high-throughput screening protease technology. J Biomol Screening95:398-408. doi: 10.1177/1087057104264040.
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