Calcium Homeostasis - PTH & Calcitonin


Calcium Homeostasis - PTH & Calcitonin

Calcium homeostasis is finely regulated by Parathyroid Hormone (PTH), Calcitonin and Vitamin D. Briefly, a decrease in calcium concentration in the blood triggers the release of PTH, an 84-amino acid hormone, from the parathyroid glands. An increase, however, causes the release of Calcitonin, a 32-amino acid protein from the thyroid parafollicular cells (C-cells).

AnaSpec carries a wide range of peptide solutions to support researchers working with Ca2+ metabolism.

For scientists in need of PTH or calcitonin peptide analogs containing unusual amino acids, AnaSpec carries a wide range of unusual amino acids that will facilitate your research. Contact us at service@anaspec.com for information about custom peptide synthesis.

PTH (1-34)
Calcitonin
Other Calcitonin related peptides:
References:

  1. Khan, MM. and JP. Desborough, Pharmacology 19, 1 (2005).
  2. Stevenson, RW and JA Parsons, J. Endo. 97, 21 (1983).
  3. Newman, W. et al. J. Biol. Chem. 264, 16359 (1989).
  4. Brennan, DP. and MA. Levine, J. Biol. Chem. 262, 14795 (1987).
  5. Broadus, AE. et al. N. Engl. J. Med. 319, 556 (1988).