Fmoc-Ser & Thr (GlcNac) for PTM Research |
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Untitled Document
Fmoc-Ser(β-D-GlcNAc(Ac)3)-OH and Fmoc-Thr(β-D-GlcNAc(Ac)3)-OH are useful building blocks for syntheses of peptides containing the GlcNAc modification of serines and threonines, respectively. The addition of β-N-acetylglucosamine (GlcNAc) to the hydroxyl group of serines or threonines generating O-linked β-N-acetylglucosamine (O-GlcNAc) serines or threonines is one kind of post-translational modification (PTM) found in proteins.1,2 This O-GlcNAcylation reversible modification directly competes with phosphorylation of these two amino acids.2,3 |
AnaSpec provides a suite of PTM amino acid building blocks to the epigenetic research community. These Fmoc amino acids that we offer to our customers are the very same amino acids that we use daily in our own manufacturing facilities. |
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To view AnaSpec's extensive collection of unusual amino acids, please click here. |
Request a free price quotation of custom PTM Peptides |
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