TR-FRET FOR LIFE SCIENCE - Custom Labeling Services & Catalog Reagents
TR-FRET for Life Science
Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) involves an energy transfer between two fluorophores in close proximity. It combines time Resolved Fluorescence (TRF) and Forster's Resonance Energy Transfer (FRET) technologies thereby offering advantages of reducing background
noise and providing higher sensitivities and reliability than FRET. TR (time-resolved) based assay technologies, as offered with our TR-FRET assay formats eliminate samples' background fluorescence by choosing a longer detection interval after excitation, thereby causing increased assay sensitivity.

Application

  • FRET/TR-FRET substrates for protease activity detection
  • Protease based drug target screening and discovery
  • Protein-peptide interaction
  • Protein-protein interaction

Benefits

  • Homogenous mix and read assay format is ideal for HTS
  • Large dynamic range
  • High sensitivity
  • Low interference

Custom & Catalog Products

    Our custom services (substrate labeling) and catalog products (labeling kits) feature,

  • Substrate labeling with Europium chelate and HiLyte™ Fluor 647.
  • AnaTag labeling kits, AnaTag Protein labeling kits, and
  • Eu/HiLyte™ Fluor 647-labeled Streptavidin and Antibodies.

  • For detailed info, please refer to our website and TR-FRET brochure.