Kinase Substrates - One of the World's Largest Collections


Protein kinases are a transferase family of self-regulatory enzymes that catalyze the phosphorylation of other proteins by covalently attaching phosphate groups to them, using ATP as a phosphate donor. Reversible protein phosphorylation-dephosphorylation has a principal role in the regulation of essentially all cellular functions and most aspects of cell life, and phosphorylation by protein kinases is a major signal transduction mechanism that regulates gene expression, proliferation, membrane transport, cell metabolism and many other cellular functions by modifiying other proteins.

To successfully assay protein kinase activity, signal transduction mechanisms, protein functions, protein detection, and many other applications, AnaSpec offers one of the world’s largest collections of protein kinase substrates. This includes phosphorylated, non- phosphorylated, biotinylated, FRET-labeled, and dye-labeled with AnaSpec’s high-performance HiLyte™ Fluor dyes and classic dyes like FAM and TAMRA.

AnaSpecs’ novel products are designed to meet the present and future needs of life science researchers and clinicians. Providing our customers with one of the world’s largest collections of kinase substrates, AnaSpec is perfecting The Science of Trust.

FamilyEnzyme
AGC (PKA, PKG, PKC) PKA (Protein Kinase A)
CREBtide [KRREILSRRPSYR], Phosphorylated, C - term K
Kemptide [LKRA - pY - LG], [Lys2, pY5]
PKC (Protein Kinase C)
PKG (Protein Kinase G)
CaMK (Calmodulin –Regulated Kinases)CaMK (Ca2+/calmodulin-dependent protein kinase)
CaMK II (Ca2+/calmodulin-dependent protein kinase II)
CMGC (CDK, MAPK, GSK, and CLK families)AKT/PKB/Rac-protein kinases
CDK5 (Cyclin-dependent Kinase 5)
CDC2
CDK1 (Cyclin-dependent protein kinase 1)
MAP kinases
Tyrosine Hydroxylase
GSK-3 (Glycogen Synthase Kinase - 3)
GSK-3ß (Glycogen Synthase Kinase - 3ß)
Glycogen Synthase
PTK (Protein Tyrosine Kinases)EGFR (Epidermal Growth Factor Receptor)
Tyrosine Kinase Peptide 1
Tyrosine Kinase Peptide 3 Platelet - Derived Growth Factor Receptor Substrate 1
Tyrosine Kinase Peptide 3
Tyrosine Kinase Peptide 3 [RRLIEDAE - pY - AARG], Amide, Phosphorylated, Biotinylated
CK (Casein Kinases)CK I (Casein Kinase I); CK II (Casein Kinase II)
Protein Phosphatases & Protein Tyrosine PhosphatasesPTP (Protein Tyrosine Phosphatase); PTP 1B (Protein Tyrosine Phosphatase 1B); Calcineurin (PP2B)
Phosphopeptides





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