plays a vital role in the regulation of cardiac contractility, growth and
gene expression; consequently, calcium measurement is critical in numerous
biological investigations. Fluorescent probes that show spectral responses
upon Ca2+ binding have enabled researchers to investigate changes
in intracellular free Ca2+ concentrations using techniques such
as fluorescence microscopy, flow cytometry, fluorescence spectroscopy. Most
of these fluorescent indicators are derivatives of BAPTA, chelators that incorporate
a photo-induced-electron transfer (PET) system responsive to calcium. Instruments,
such as FLIPR® and FlexStationTM have enabled high throughput measurement
of calcium for GPCR and ion channel research.
is pleased to highlight a selection of fluorescent Ca2+ indicators.
These calcium indicators are of the highest quality and are cost-effective.
They include UV-excitable and visible light-excitable calcium indicators.
the UV-excitable calcium indicators, Fura-2 and Indo-1 are the most commonly
used. Rhod-2 is among the most commonly used among the visible light-excitable
inquire about licensing opportunities for AnaSpec dyes, please email
UV-Excitable Calcium Indicators
Visible Light-Excitable Calcium Indicators
News: BD chooses AnaSpec
to manufacture and supply the BDTM H7, Calcein AM and DiIC12(3)