Peptides

26Rfa, Hypothalamic Peptide, human - 1 mg

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  • Cat.Number : AS-61651
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26Rfa is a neuropeptide belonging to the RFamide peptide family. It exhibits orexigenic activity and has been associated to obesity. The primary structures of human, rat, and frog 26RFa exhibit 80% identity, and the C-terminal octapeptide is fully conserved from amphibians to mammals.

Specifications

Chemistry
Sequence one letter code
  • TSGPLGNLAEELNGYSRKKGGFSFRF-NH2
Sequence three letter code
  • H-Thr-Ser-Gly-Pro-Leu-Gly-Asn-Leu-Ala-Glu-Glu-Leu-Asn-Gly-Tyr-Ser-Arg-Lys-Lys-Gly-Gly-Phe-Ser-Phe-Arg-Phe-NH2
CAS registry number
  • 600171-68-4
Molecular Formula
  • C127H195N37O37
Molecular Mass/ Weight
  • 2832.3
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

Identification of 26RFa, a hypothalamic neuropeptide of the RFamide peptide family with orexigenic activity

PNAS . 2003 Dec 09 ; 100(25) 15247 | DOI : https://doi.org/10.1073/pnas.2434676100

  • N. Chartrel
  • et al

Novel role of 26RFa, a hypothalamic RFamide orexigenic peptide, as putative regulator of the gonadotropic axis

J Physiol . 2006 May 09 ; 573(1) 237 | DOI : https://doi.org/10.1113/jphysiol.2006.106856

  • V. Navarro
  • et al